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Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer

Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can be an effective approach for cancer therapy. We focused on silencing the angiogenic gene PLXDC1 as an important factor for anti-angiogenesis tumor therapy. Herein, we developed PL...

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Dades bibliogràfiques
Publicat a:Drug Deliv
Autors principals: Kim, Ga Hee, Won, Ji Eun, Byeon, Yeongseon, Kim, Min Gi, Wi, Tae In, Lee, Jae Myeong, Park, Yun-Yong, Lee, Jeong-Won, Kang, Tae Heung, Jung, In Duk, Shin, Byung Cheol, Ahn, Hyung Jun, Lee, Young Joo, Sood, Anil K., Han, Hee Dong, Park, Yeong-Min
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096458/
https://ncbi.nlm.nih.gov/pubmed/29890852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1480672
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