Autophagy inhibitor chloroquine induces apoptosis of cholangiocarcinoma cells via endoplasmic reticulum stress

Poor prognosis and chemotherapy tolerance are the main obstacles encountered in the treatment of cholangiocarcinoma. Chloroquine (CQ), an antimalarial agent, is able to induce sustained endoplasmic reticulum (ER) stress by functioning as an autophagy inhibitor. The present study indicated that CQ ha...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Jia, Baoxing, Xue, Yanan, Yan, Xiaoyu, Li, Jiuling, Wu, Yao, Guo, Rui, Zhang, Juanjuan, Zhang, Lichao, Li, Yaping, Liu, Yahui, Sun, Liankun
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096195/
https://ncbi.nlm.nih.gov/pubmed/30127955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9131
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