Autophagy inhibitor chloroquine induces apoptosis of cholangiocarcinoma cells via endoplasmic reticulum stress

Poor prognosis and chemotherapy tolerance are the main obstacles encountered in the treatment of cholangiocarcinoma. Chloroquine (CQ), an antimalarial agent, is able to induce sustained endoplasmic reticulum (ER) stress by functioning as an autophagy inhibitor. The present study indicated that CQ ha...

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Vydáno v:Oncol Lett
Hlavní autoři: Jia, Baoxing, Xue, Yanan, Yan, Xiaoyu, Li, Jiuling, Wu, Yao, Guo, Rui, Zhang, Juanjuan, Zhang, Lichao, Li, Yaping, Liu, Yahui, Sun, Liankun
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096195/
https://ncbi.nlm.nih.gov/pubmed/30127955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9131
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