Neuropathic Pain Creates an Enduring Prefrontal Cortex Dysfunction Corrected by the Type II Diabetic Drug Metformin But Not by Gabapentin

Chronic pain patients suffer from pain-related cognitive deficits, even when taking commonly prescribed analgesics. These deficits are likely related to pain-related maladaptive plasticity in the frontal cortex. We sought to model cognitive deficits in mice with neuropathic pain to examine maladapti...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shiers, Stephanie, Pradhan, Grishma, Mwirigi, Juliet, Mejia, Galo, Ahmad, Ayesha, Kroener, Sven, Price, Theodore
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096044/
https://ncbi.nlm.nih.gov/pubmed/30030404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0713-18.2018
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