Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model

The dopaminergic hypothesis of schizophrenia (SZ) postulates that dopaminergic over activity causes psychosis, a central feature of SZ, based on the observation that blocking dopamine (DA) improves psychotic symptoms. DA is known to have both receptor- and non-receptor-mediated effects, including ox...

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Foilsithe in:Transl Psychiatry
Main Authors: Duan, Jubao, Göring, Harald H. H., Sanders, Alan R., Moy, Winton, Freda, Jessica, Drigalenko, Eugene I., Kos, Mark, He, Deli, Gejman, Pablo V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095865/
https://ncbi.nlm.nih.gov/pubmed/30115913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0216-5
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