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Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model

The dopaminergic hypothesis of schizophrenia (SZ) postulates that dopaminergic over activity causes psychosis, a central feature of SZ, based on the observation that blocking dopamine (DA) improves psychotic symptoms. DA is known to have both receptor- and non-receptor-mediated effects, including ox...

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Bibliografische gegevens
Gepubliceerd in:Transl Psychiatry
Hoofdauteurs: Duan, Jubao, Göring, Harald H. H., Sanders, Alan R., Moy, Winton, Freda, Jessica, Drigalenko, Eugene I., Kos, Mark, He, Deli, Gejman, Pablo V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095865/
https://ncbi.nlm.nih.gov/pubmed/30115913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0216-5
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