Chronic neuropathic pain reduces opioid receptor availability with associated anhedonia in rat

The opioid system plays a critical role in both the experience and management of pain. Although acute activation of the opioid system can lead to pain relief, the effects of chronic pain on the opioid system remain opaque. Cross-sectional positron emission tomography (PET) studies show reduced avail...

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Dettagli Bibliografici
Pubblicato in:Pain
Autori principali: Thompson, Scott J., Pitcher, Mark H., Stone, Laura S., Tarum, Farid, Niu, Gang, Chen, Xiaoyuan, Kiesewetter, Dale O., Schweinhardt, Petra, Bushnell, M. Catherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095806/
https://ncbi.nlm.nih.gov/pubmed/29794614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001282
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