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The HMW2 adhesin of non-typeable Haemophilus influenzae is a human-adapted lectin that mediates high-affinity binding to 2-6 linked N-acetylneuraminic acid glycans

Non-typeable Haemophilus influenzae (NTHi) is a human-adapted bacterial pathogen, responsible for infections of the human respiratory tract. This pathogen expresses a range of adhesins that mediate binding to host cells. Most NTHi strains can express the related adhesins HMW1 and HMW2. Expression of...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Atack, John M, Day, Christopher J, Poole, Jessica, Brockman, Kenneth L., Bakaletz, Lauren O, Barenkamp, Stephen J, Jennings, Michael P
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095747/
https://ncbi.nlm.nih.gov/pubmed/29944882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.06.126
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