Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism

We previously discovered that phytonutrient genistein rapidly activates cAMP signaling in β-cells and improving islet mass in diabetic mice. However, the mechanism underlying these actions of genistein is still unclear. Here, we show that pharmacological or molecular inhibition of Gαs blocked genist...

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Publicado no:J Nutr Biochem
Main Authors: Luo, Jing, Wang, Aihua, Zhen, Wei, Wang, Yao, Si, Hongwei, Jia, Zhenquan, Alkhalidy, Hana, Cheng, Zhiyong, Gilbert, Elizabeth, Xu, Bin, Liu, Dongmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095734/
https://ncbi.nlm.nih.gov/pubmed/29885598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2018.04.018
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