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Effects of Exercise on ASC Methylation and IL-1 Cytokines in Heart Failure

INTRODUCTION/PURPOSE: Inflammation contributes to heart failure (HF) progression and the interleukin (IL)-1 cytokine IL-1β is implicated in this process. The adaptor protein ASC is necessary for inflammasome activation of IL-1β. Lower ASC methylation is associated with worse outcomes in HF. The purp...

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Bibliographic Details
Published in:Med Sci Sports Exerc
Main Authors: Butts, Brittany, Butler, Javed, Dunbar, Sandra B, Corwin, Elizabeth, Gary, Rebecca A
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095733/
https://ncbi.nlm.nih.gov/pubmed/29683921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1249/MSS.0000000000001641
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