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Conducting efficacy trials in children with multidrug-resistant tuberculosis: what is the rationale and how should they be done?
Traditionally paediatric tuberculosis (TB) treatment trials have been limited to phase I/II studies evaluating the pharmacokinetics and safety of drugs in children, with assumptions about efficacy made by extrapolating data from adults. However, it is increasingly recognised that in some circumstanc...
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| 出版年: | Int J Tuberc Lung Dis |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6095656/ https://ncbi.nlm.nih.gov/pubmed/29665950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5588/ijtld.17.0359 |
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