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Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum

There is need for a more efficient cell-based assay amenable to high-throughput drug screening against Giardia lamblia. Here, we report the development of a screening method utilizing G. lamblia engineered to express red-shifted firefly luciferase. Parasite growth and replication were quantified usi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Negl Trop Dis
Päätekijät: Hennessey, Kelly M., Rogiers, Ilse C., Shih, Han-Wei, Hulverson, Matthew A., Choi, Ryan, McCloskey, Molly C., Whitman, Grant R., Barrett, Lynn K., Merritt, Ethan A., Paredez, Alexander R., Ojo, Kayode K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095626/
https://ncbi.nlm.nih.gov/pubmed/30080847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006673
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