Co-expression of CD21L and IL17A defines a subset of rheumatoid synovia, characterised by large lymphoid aggregates and high inflammation

OBJECTIVE: To determine whether the expression of IL17A and CD21L genes in inflamed rheumatoid synovia is associated with the neogenesis of ectopic lymphoid follicle-like structures (ELS), and if this aids the stratification of rheumatoid inflammation and thereby distinguishes patients with rheumato...

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Udgivet i:PLoS One
Main Authors: McKelvey, Kelly J., Millier, Melanie J., Doyle, Terence C., Stamp, Lisa K., Highton, John, Hessian, Paul A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095528/
https://ncbi.nlm.nih.gov/pubmed/30114200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202135
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