MKRN2 inhibits migration and invasion of non-small-cell lung cancer by negatively regulating the PI3K/Akt pathway

BACKGROUND: Makorin RING zinc finger-2 (MKRN2) belongs to the makorin RING zinc finger family and is a novel ubiquitin E3 ligase targeting the p65 subunit of NF-κB to negatively regulate inflammatory responses; however, the relationship between MKRN2 and tumorigenesis remains unclear. In this study,...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Jiang, Jun, Xu, Yitong, Ren, Hongjiu, Wudu, Muli, Wang, Qiongzi, Song, Xin, Su, Hongbo, Jiang, Xizi, Jiang, Lihong, Qiu, Xueshan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090690/
https://ncbi.nlm.nih.gov/pubmed/30103781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0855-7
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