Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment

BACKGROUND: The irinotecan-induced phosphokinome changes in colorectal cancer (CRC) cells were used to guide the selection of targeted agents to be tested in combination with irinotecan. METHODS: Phosphokinome profiling with peptide arrays of tumour samples from nude mice xenografted with HT29 cells...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Tosi, Diego, Pérez-Gracia, Esther, Atis, Salima, Vié, Nadia, Combès, Eve, Gabanou, Mélissa, Larbouret, Christel, Jarlier, Marta, Mollevi, Caroline, Torro, Adeline, Del Rio, Maguy, Martineau, Pierre, Gongora, Céline
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090616/
https://ncbi.nlm.nih.gov/pubmed/30103709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4712-z
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