Triheteromeric GluN1/GluN2A/GluN2C NMDARs with unique single channel properties are the dominant receptor population in cerebellar granule cells

NMDA-type glutamate receptors (NMDARs) are ligand-gated ion channels that mediate excitatory neurotransmission in the central nervous system (CNS). Here, we describe functional and single channel properties of triheteromeric GluN1/GluN2A/GluN2C receptors, which contain two GluN1, one GluN2A, and one...

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Udgivet i:Neuron
Main Authors: Bhattacharya, Subhrajit, Khatri, Alpa, Swanger, Sharon A., DiRaddo, John O., Yi, Feng, Hansen, Kasper B., Yuan, Hongjie, Traynelis, Stephen F.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090556/
https://ncbi.nlm.nih.gov/pubmed/30056832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.06.010
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