Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue

The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clinicians, exert toxic effects on human primary nucleus pulposus (NP) and annulus fibrosis (AF). Primary human cell cultures were obtained...

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Udgivet i:Exp Ther Med
Main Authors: Karaarslan, Numan, Yilmaz, Ibrahim, Sirin, Duygu Yasar, Ozbek, Hanefi, Kaplan, Necati, Kaya, Yasin Emre, Akyuva, Yener, Gurbuz, Mehmet Sabri, Oznam, Kadir, Ates, Ozkan
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090477/
https://ncbi.nlm.nih.gov/pubmed/30112057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6289
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