Oxidative Stress Mediates Microcystin-LR-Induced Endoplasmic Reticulum Stress and Autophagy in KK-1 Cells and C57BL/6 Mice Ovaries

Microcystin-leucine arginine (MC-LR) is a cyclic heptapeptide intracellular toxin released by cyanobacteria that exhibits strong reproductive toxicity. However, little is known about its biotoxicity to the female reproductive system. The present study investigates unexplored molecular pathways by wh...

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Liu, Haohao, Zhang, Xiaofeng, Zhang, Shenshen, Huang, Hui, Wu, Jinxia, Wang, Yueqin, Yuan, Le, Liu, Chuanrui, Zeng, Xin, Cheng, Xuemin, Zhuang, Donggang, Zhang, Huizhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090159/
https://ncbi.nlm.nih.gov/pubmed/30131715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01058
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