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Quinolone-fused cyclic sulfonamide as a novel benign antifilarial agent

Search of potent antifilarial drugs has been a major thrust area in tropical medicine research over the decades. Herein, we report 4,7-dimethyl-3,4,7,8-tetrahydro-3λ(6)-[1,2]thiazino[4,3-f]quinoline-3,3,8-trione (8l) as a new class of antifilarial agent which is extremely potent, with lethality agai...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mukherjee, Suprabhat, Joardar, Nikhilesh, Mondal, Shovan, Schiefer, Andrea, Hoerauf, Achim, Pfarr, Kenneth, Babu, Santi P. Sinha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089915/
https://ncbi.nlm.nih.gov/pubmed/30104608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30610-7
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