Pharmacokinetics and safety of fluconazole and micafungin in neonates with systemic candidiasis: a randomized, open‐label clinical trial

AIMS: The pharmacokinetics (PK) of fluconazole and micafungin differ in neonates compared with children and adults. Dosing instructions in product labels appear to be inconsistent with the emerging scientific evidence. Limited information is available on the safety profile of these agents in neonate...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Leroux, S., Jacqz‐Aigrain, E., Elie, V., Legrand, F., Barin‐Le Guellec, C., Aurich, B., Biran, V., Dusang, B., Goudjil, S., Coopman, S., Garcia Sanchez, R., Zhao, W., Manzoni, P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089805/
https://ncbi.nlm.nih.gov/pubmed/29744900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13628
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