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Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart

The mechanism underlying the anti-inflammatory or antifibrotic activity of erythropoietin (EPO) in myocardial fibrosis (MF) remains elusive. In the current study, abdominal aortic constriction (AAC) was performed on rats and EPO and/or Toll-like receptor (TLR)4 were overexpressed in rat hearts throu...

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Vydáno v:Int J Mol Med
Hlavní autoři: Liu, Fei, Wen, Yuan, Kang, Jinyuan, Wei, Chunying, Wang, Menghong, Zheng, Zeqi, Peng, Jingtian
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089778/
https://ncbi.nlm.nih.gov/pubmed/29845292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3707
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