Association between acute respiratory disease events and the MUC5B promoter polymorphism in smokers

A single-nucleotide polymorphism (rs35705950) in the mucin 5B (MUC5B) gene promoter is associated with pulmonary fibrosis and interstitial features on chest CT but may also have beneficial effects. In non-Hispanic whites in the COPDGene cohort with interstitial features (n=454), the MUC5B promoter p...

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Publicado no:Thorax
Main Authors: Ash, Samuel Y, Harmouche, Rola, Putman, Rachel K, Ross, James C, Martinez, Fernando J, Choi, Augustine M, Bowler, Russell P, Regan, Elizabeth A, Curtis, Jeffrey L, Han, MeiLan K, Boucher, Richard C, O’Neal, Wanda K, Hatabu, Hiroto, Lynch, David A, Rosas, Ivan O, Hunninghake, Gary M, Estepar, Raul San Jose, Washko, George R
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089672/
https://ncbi.nlm.nih.gov/pubmed/29440587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2017-211208
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