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Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos

Regulating nuclear histone balance is essential for survival, yet in early Drosophila melanogaster embryos many regulatory strategies employed in somatic cells are unavailable. Previous work had suggested that lipid droplets (LDs) buffer nuclear accumulation of the histone variant H2Av. Here, we elu...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Johnson, Matthew Richard, Stephenson, Roxan Amanda, Ghaemmaghami, Sina, Welte, Michael Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089599/
https://ncbi.nlm.nih.gov/pubmed/30044219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36021
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