Stim and Orai mediate constitutive Ca(2+) entry and control endoplasmic reticulum Ca(2+) refilling in primary cultures of colorectal carcinoma cells

Store-operated Ca(2+) entry (SOCE) provides a major Ca(2+) entry route in cancer cells. SOCE is mediated by the assembly of Stim and Orai proteins at endoplasmic reticulum (ER)-plasma membrane junctions upon depletion of the ER Ca(2+) store. Additionally, Stim and Orai proteins underpin constitutive...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zuccolo, Estella, Laforenza, Umberto, Ferulli, Federica, Pellavio, Giorgia, Scarpellino, Giorgia, Tanzi, Matteo, Turin, Ilaria, Faris, Pawan, Lucariello, Angela, Maestri, Marcello, Kheder, Dlzar Ali, Guerra, Germano, Pedrazzoli, Paolo, Montagna, Daniela, Moccia, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089563/
https://ncbi.nlm.nih.gov/pubmed/30123430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25785
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