MyD88 activation in cardiomyocytes contributes to the heart immune response to acute Trypanosoma cruzi infection with no effect on local parasite control

Cardiomyopathy is the most serious consequence of Chagas disease, a neglected human disorder caused by Trypanosoma cruzi infection. Because T. cruzi parasites invade cardiomyocytes, we sought to investigate whether these cells recognize the parasite in vivo by receptors signaling through the MyD88 a...

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Publicado en:PLoS Negl Trop Dis
Autores principales: Santana, Danni Yohani, Salgado, Rafael Moysés, Fevereiro, Marina, Silva do Nascimento, Rogério, Fonseca, Raissa, Saraiva Câmara, Niels Olsen, Epiphanio, Sabrina, Marinho, Cláudio Romero Farias, Barreto-Chaves, Maria Luiza, D’ Império-Lima, Maria Regina, Álvarez, José M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089445/
https://ncbi.nlm.nih.gov/pubmed/30067739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006617
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