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A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein

Spinal muscular atrophy (SMA) is a severe genetic neuromuscular disorder caused by insufficiency of functional survival motor neuron (SMN) protein. Several clinical trials have been conducted with the aim of upregulating the expression of the SMN protein in SMA patients. In order to evaluate the eff...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Otsuki, Noriko, Arakawa, Reiko, Kaneko, Kaori, Aoki, Ryoko, Arakawa, Masayuki, Saito, Kayoko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089418/
https://ncbi.nlm.nih.gov/pubmed/30102724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201764
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