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Identification of Positively and Negatively Selected Driver Gene Mutations Associated With Colorectal Cancer With Microsatellite Instability
BACKGROUND & AIMS: Recent studies have shown that cancers arise as a result of the positive selection of driver somatic events in tumor DNA, with negative selection playing only a minor role, if any. However, these investigations were concerned with alterations at nonrepetitive sequences and did...
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| Опубликовано в: : | Cell Mol Gastroenterol Hepatol |
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| Главные авторы: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089198/ https://ncbi.nlm.nih.gov/pubmed/30116770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.06.002 |
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