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The expression of the γ subunit of Na-K-ATPase is regulated by osmolality via C-terminal Jun kinase and phosphatidylinositol 3-kinase-dependent mechanisms

The α and β subunits of Na-K-ATPase are up-regulated by hypertonicity in inner-medullary collecting duct cells adapted to survive in hypertonic conditions. We examined the regulation of the γ subunit by hypertonicity. Although cultured inner-medullary collecting duct cells lacked the γ subunits, bot...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Capasso, J. M., Rivard, C., Berl, T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60885/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11687620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231309198
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