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Optical molecular imaging of lysyl oxidase activity – detection of active fibrogenesis in human lung tissue
Aberrant fibrogenesis is a feature of many diseases in multiple organ systems. The lysyl oxidase family of enzymes are central to tissue homeostasis and elevated lysyl oxidase activity is implicated in fibroproliferation as well as in cancer stroma. We have synthesised a novel fluorogenic reporter f...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6088439/ https://ncbi.nlm.nih.gov/pubmed/30155003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01258a |
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