Pioglitazone Protects Against Renal Ischemia-Reperfusion Injury via the AMP-Activated Protein Kinase-Regulated Autophagy Pathway

Renal ischemia-reperfusion injury (IRI) is a major cause of acute renal failure. Our previous studies have shown that pioglitazone, a peroxisome proliferators-activated receptor (PPAR)-γ agonist used in type 2 diabetes, protects against renal IRI; however, the molecular mechanism underlying the reno...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Chen, Wenlin, Xi, Xiaoqing, Zhang, Shuangyang, Zou, Cong, Kuang, Renrui, Ye, Zhenfeng, Huang, Yawei, Hu, Honglin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088275/
https://ncbi.nlm.nih.gov/pubmed/30127742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00851
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