Impact of Flow Rate, Collection Devices, and Extraction Methods on Tear Concentrations Following Oral Administration of Doxycycline in Dogs and Cats

Purpose: Compare the precision of doxycycline quantification in tear fluid collected with either Schirmer strips or polyvinyl acetal (PVA) sponges following oral drug administration. Methods: Three dogs and 3 cats were administered doxycycline orally at a dose of 4.2–5 mg/kg every 12 h for 6 consecu...

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Bibliographische Detailangaben
Veröffentlicht in:J Ocul Pharmacol Ther
Hauptverfasser: Sebbag, Lionel, Showman, Lucas, McDowell, Emily M., Perera, Ann, Mochel, Jonathan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088255/
https://ncbi.nlm.nih.gov/pubmed/29708819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2018.0008
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