Effect of a melanocortin type 2 receptor (MC2R) antagonist on the corticosterone response to hypoxia and ACTH stimulation in the neonatal rat

The adrenal stress response in the neonatal rat shifts from ACTH-independent to ACTH-dependent between postnatal days 2 (PD2) and 8 (PD8). This may be due to an increase in an endogenous, bioactive, nonimmunoreactive ligand to the melanocortin type 2 receptor (MC2R). GPS1574 is a newly described MC2...

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Bibliografiset tiedot
Julkaisussa:Am J Physiol Regul Integr Comp Physiol
Päätekijät: Goldenberg, Adam J., Gehrand, Ashley L., Waples, Emily, Jablonski, Mack, Hoeynck, Brian, Raff, Hershel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2018
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Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087887/
https://ncbi.nlm.nih.gov/pubmed/29718699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00009.2018
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