Peripheral T Cell Depletion by FTY720 Exacerbates Hypoxic-Ischemic Brain Injury in Neonatal Mice

Hypoxic-ischemic injury to the developing brain remains a major cause of significant long-term morbidity and mortality. Emerging evidence from neonatal brain injury models suggests a detrimental role for peripheral lymphocytes. The immunomodulatory substance FTY720, a sphingosine-1-phosphate recepto...

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Vydáno v:Front Immunol
Hlavní autoři: Herz, Josephine, Köster, Christian, Crasmöller, Marius, Abberger, Hanna, Hansen, Wiebke, Felderhoff-Müser, Ursula, Bendix, Ivo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087766/
https://ncbi.nlm.nih.gov/pubmed/30127782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01696
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