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Report of the Third Family with Multiple Mitochondrial Dysfunctions Syndrome 5 Caused by the Founder Variant p.(Glu87Lys) in ISCA1

Iron-sulfur cluster assembly 1 (ISCA1) is one of the essential proteins operating in the mitochondrial iron-sulfur (Fe-S) cluster biogenesis pathway. We reported the variant c.259G > A [p.(Glu87Lys)] in homozygous state in exon 4 of the ISCA1 gene as the likely cause of multiple mitochondrial dys...

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Detalhes bibliográficos
Publicado no:J Pediatr Genet
Main Authors: Shukla, Anju, Kaur, Parneet, Girisha, Katta M.
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087475/
https://ncbi.nlm.nih.gov/pubmed/30105122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1641177
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