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Oxidative Stress and Polymorphism in MTHFR SNPs (677 and 1298) in Paternal Sperm DNA is Associated with an Increased Risk of Retinoblastoma in Their Children: A Case–Control Study
Sperm DNA is considered as the most vulnerable to oxidative stress-induced damage that also impairs global sperm DNA methylation leading to sperm-associated pathologies. C677T and A1298C polymorphisms of the methylene tetrahydrofolate reductase (MTHFR) gene affect MTHFR enzyme activity. This study w...
Tallennettuna:
| Julkaisussa: | J Pediatr Genet |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Georg Thieme Verlag KG
2018
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087474/ https://ncbi.nlm.nih.gov/pubmed/30105117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1667037 |
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