Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse

Diabetic nephropathy is a major risk factor for end-stage renal disease and cardiovascular diseases and has a marked genetic component. A common variant (D allele) of the angiotensin Iconverting enzyme (ACE) gene, determining higher enzyme levels, has been associated with diabetic nephropathy. To ad...

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Bibliographische Detailangaben
Hauptverfasser: Huang, Wei, Gallois, Yves, Bouby, Nadine, Bruneval, Patrick, Heudes, Didier, Belair, Marie-France, Krege, John H., Meneton, Pierre, Marre, Michel, Smithies, Oliver, Alhenc-Gelas, François
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60870/
https://ncbi.nlm.nih.gov/pubmed/11687636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231476798
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