Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging

A highly multiplexed cytometric imaging approach, termed co-detection by indexing (CODEX), is used here to create multiplexed datasets of normal and lupus (MRL/lpr) murine spleens. CODEX iteratively visualizes antibody binding events using DNA barcodes, fluorescent dNTP analogs, and an in situ polym...

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Bibliographic Details
Published in:Cell
Main Authors: Goltsev, Yury, Samusik, Nikolay, Kennedy-Darling, Julia, Bhate, Salil, Hale, Matthew, Vazquez, Gustavo, Black, Sarah, Nolan, Garry P.
Format: Artigo
Language:Inglês
Published: Cell Press 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086938/
https://ncbi.nlm.nih.gov/pubmed/30078711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.07.010
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