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Enzyme-modified non-oxidized LDL (ELDL) induces human coronary artery smooth muscle cell transformation to a migratory and osteoblast-like phenotype

Enzyme modified non-oxidative LDL (ELDL) is effectively taken up by vascular smooth muscle cells (SMC) and mediates transition into foam cells and produces phenotypic changes in SMC function. Our data show that incubation of human coronary artery SMC (HCASMC) with low concentration of ELDL (10 μg/ml...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chellan, Bijoy, Rojas, Elizabeth, Zhang, Chunling, Hofmann Bowman, Marion A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086911/
https://ncbi.nlm.nih.gov/pubmed/30097618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30073-w
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