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QTc prolongation in hospitalized pediatric patients receiving methadone

OBJECTIVE: Methadone is often used in pediatric patients to prevent or treat opioid withdrawal after prolonged sedation. Prolonged QTc is an important adverse effect of methadone because it can progress to torsades de pointes (TdP), a potentially fatal dysrhythmia. The incidence of QTc prolongation...

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Pubblicato in:Pediatr Crit Care Med
Autori principali: Schwinghammer, Amy J., Wilson, Machelle D., Hall, Brent A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086758/
https://ncbi.nlm.nih.gov/pubmed/29894447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0000000000001601
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