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Investigating the disease association of USH2A p.C759F variant by leveraging large retinitis pigmentosa cohort data

Retinitis pigmentosa (RP) is an inherited retinal disease with a prevalence of 1/4,000. RP is highly genetically heterogeneous and there are over 80 genes associated with RP to date. One particular USH2A variant, p.C759F, has long been reported in RP cases but its pathogenicity was questioned by a r...

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Podrobná bibliografie
Vydáno v:Ophthalmic Genet
Hlavní autoři: DuPont, Mariana, Jones, Evan M., Xu, Mingchu, Chen, Rui
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084783/
https://ncbi.nlm.nih.gov/pubmed/29283788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13816810.2017.1418388
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