Loading...

Dynamics of Dystrophin’s Actin-Binding Domain

We have used pulsed electron paramagnetic resonance, calorimetry, and molecular dynamics simulations to examine the structural mechanism of binding for dystrophin’s N-terminal actin-binding domain (ABD1) and compare it to utrophin’s ABD1. Like other members of the spectrin superfamily, dystrophin’s...

Full description

Saved in:
Bibliographic Details
Published in:Biophys J
Main Authors: Fealey, Michael E., Horn, Benjamin, Coffman, Christian, Miller, Robert, Lin, Ava Y., Thompson, Andrew R., Schramel, Justine, Groth, Erin, Hinderliter, Anne, Cembran, Alessandro, Thomas, David D.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084637/
https://ncbi.nlm.nih.gov/pubmed/30007583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.05.039
Tags: Add Tag
No Tags, Be the first to tag this record!