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Bioequivalence and Safety of Twice‐Daily Sustained‐Release Paracetamol (Acetaminophen) Compared With 3‐ and 4‐Times‐Daily Paracetamol: A Repeat‐Dose, Crossover Pharmacokinetic Study in Healthy Volunteers

Twice‐daily sustained‐release (SR) paracetamol (acetaminophen) offers convenient administration to chronic users. This study investigated at steady state (during the last 24 hours of a 3‐day dosing period) the pharmacokinetics, bioequivalence, and safety of twice‐daily SR paracetamol compared with e...

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Bibliographic Details
Published in:Clin Pharmacol Drug Dev
Main Authors: Liu, Dongzhou J., Collaku, Agron
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084369/
https://ncbi.nlm.nih.gov/pubmed/28815997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.369
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