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Patterns of response to crizotinib in recurrent glioblastoma according to ALK and MET molecular profile in two patients
Two patients with an unmethylated MGMT promoter and IDH1 (R132H) wild-type recurrent glioblastoma were treated with crizotinib. Prolonged stabilization of the disease (17 months) was achieved in the first case. Interestingly, anaplastic lymphoma kinase (ALK) expression and c-MET protein overexpressi...
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| Wydane w: | CNS Oncol |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Future Medicine Ltd
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6083940/ https://ncbi.nlm.nih.gov/pubmed/26498130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns.15.30 |
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