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Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae

Mosaic interspecifically acquired alleles of the multiple transferable resistance (mtr) efflux pump operon correlate with increased resistance to azithromycin in Neisseria gonorrhoeae in epidemiological studies. However, whether and how these alleles cause resistance is unclear. Here, we use populat...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Wadsworth, Crista B., Arnold, Brian J., Sater, Mohamad R. Abdul, Grad, Yonatan H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083905/
https://ncbi.nlm.nih.gov/pubmed/30087172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01419-18
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