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Design, synthesis and biological evaluation of 3′,4′,5′-trimethoxy flavonoid benzimidazole derivatives as potential anti-tumor agents

A series of 3′,4′,5′-trimethoxy flavonoids with benzimidazole linked by different chain alkanes have been designed and synthesized. The potential activity of these compounds as anti-tumor agents was evaluated by cytotoxicity assay in MGC-803 (human gastric cancer), MCF-7 (human breast cancer), HepG-...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Wang, Zhe, Deng, Xiangping, Xiong, Runde, Xiong, Shujuan, Liu, Juan, Cao, Xuan, Lei, Xiaoyong, Chen, Yanming, Zheng, Xing, Tang, Guotao
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083785/
https://ncbi.nlm.nih.gov/pubmed/30108924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00578d
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