P19 Cells as a Model for Studying the Circadian Clock in Stem Cells before and after Cell Differentiation

In mammals, circadian rhythmicity is sustained via a transcriptional/translational feedback loop referred to as the canonical molecular circadian clock. Circadian rhythm is absent in undifferentiated embryonic stem cells; it begins only after differentiation. We used pluripotent P19 embryonal carcin...

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Bibliographic Details
Published in:J Circadian Rhythms
Main Authors: Mashhour, Abdullah, Al Mansour, Zainab, Al Hallaj, Al Shaima, Ali, Rizwan, Trivilegio, Thadeo, Boudjelal, Mohamed
Format: Artigo
Language:Inglês
Published: Ubiquity Press 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083773/
https://ncbi.nlm.nih.gov/pubmed/30210566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5334/jcr.157
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