Combining mGRASP and Optogenetics Enables High-Resolution Functional Mapping of Descending Cortical Projections

We have applied optogenetics and mGRASP, a light microscopy technique that labels synaptic contacts, to map the number and strength of defined corticocollicular (CC) connections. Using mGRASP, we show that CC projections form small, medium, and large synapses, and both the number and the distributio...

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Pubblicato in:Cell Rep
Autori principali: Song, Jun Ho, Lucaci, Diana, Calangiu, Ioana, Brown, Matthew T.C., Park, Jin Sung, Kim, Jinhyun, Brickley, Stephen G., Chadderton, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083038/
https://ncbi.nlm.nih.gov/pubmed/30044974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.076
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