The Human Heart Contains Distinct Macrophage Subsets with Divergent Origins and Functions

Paradigm shifting studies in the mouse have identified tissue macrophage heterogeneity as a critical determinant of immune responses. In contrast, surprisingly little is known regarding macrophage heterogeneity in humans. Macrophages within the mouse heart are partitioned into CCR2- and CCR2+ subset...

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Bibliographic Details
Published in:Nat Med
Main Authors: Bajpai, Geetika, Schneider, Caralin, Wong, Nicole, Bredemeyer, Andrea, Hulsmans, Maarten, Nahrendorf, Matthias, Epelman, Slava, Kreisel, Daniel, Liu, Yongjoan, Itoh, Akinobu, Shankar, Thirupura S., Selzman, Craig H., Drakos, Stavros G., Lavine, Kory J.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082687/
https://ncbi.nlm.nih.gov/pubmed/29892064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0059-x
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