Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens

The high susceptibility of neonates to infections has been assumed to be due to immaturity of the immune system, but the mechanism remains unclear. By colonizing adult germ-free mice with the cecal contents of neonatal and adult mice, we show that the neonatal microbiota is unable to prevent coloniz...

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Pubblicato in:Science
Autori principali: Kim, Yun-Gi, Sakamoto, Kei, Seo, Sang-Uk, Pickard, Joseph M., Gillilland, Merritt G., Pudlo, Nicholas A., Hoostal, Matthew, Li, Xue, Wang, Thomas D., Feehley, Taylor, Stefka, Andrew T., Schmidt, Thomas M., Martens, Eric C., Fukuda, Shinji, Inohara, Naohiro, Nagler, Cathryn R., Núñez, Gabriel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082366/
https://ncbi.nlm.nih.gov/pubmed/28428425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aag2029
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