Atorvastatin mitigates cyclophosphamide-induced hepatotoxicity via suppression of oxidative stress and apoptosis in rat model

Cyclophosphamide (CP), as a chemotherapy drug, induces hepatotoxicity through causing oxidative stress. Atorvastatin (ATV) at a low dose has antioxidant and anti-inflammatory properties. The present study was designed to investigate the protective effects of ATV against CP-induced hepatotoxicity in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Res Pharm Sci
Main Authors: Hamzeh, Maedeh, Hosseinimehr, Seyed Jalal, Khalatbary, Ali Reza, Mohammadi, Hamid Reza, Dashti, Ayat, Amiri, Fereshteh Talebpour
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2018
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082033/
https://ncbi.nlm.nih.gov/pubmed/30271446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.236837
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