Leishmania donovani induced Unfolded Protein Response delays host cell apoptosis in PERK dependent manner

BACKGROUND: Endoplasmic reticulum (ER) stress generated unfolded stress response (UPR) is a basic survival mechanism which protects cell under unfavourable conditions. Leishmania parasite modulates host macrophages in various ways to ensure its survival. Modulation of PI3K-Akt pathway in delayed apo...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Abhishek, Kumar, Das, Sushmita, Kumar, Ashish, Kumar, Ajay, Kumar, Vinod, Saini, Savita, Mandal, Abhishek, Verma, Sudha, Kumar, Manjay, Das, Pradeep
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081962/
https://ncbi.nlm.nih.gov/pubmed/30036391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006646
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